Giant aneurysms (higher than eight mm or the diameter of the aorta) pose a most severe problem. Acquired melanonychias are usually not wider than 5 mm, although they might widen insidiously and even abruptly to occupy almost the whole nail width. Histopathology reveals increased marginal zones and follicles and extramedullary haematopoiesis within the spleen and increased numbers of high endothelial venules in mesenteric lymph nodes and popliteal lymph nodes (Vos et al skin care network barnet ltd
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