Vitamin D receptors from patients with resistance to 1,25-dihydroxyvitamin D3: point mutations confer reduced transactivation in response to ligand and impaired interplay with the retinoid X receptor heterodimeric associate. A proliferation of interstitial cells and a reduction in the number and motility of spermatozoa was noticed following chronic publicity (6 months) of an oral dose of 2. Pairwise comparisons of the allele and heterozygote frequencies (observed heterozygosity, Hobs) in the group of breeds studied have been performed utilizing the Fisher actual check
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